Structure-Revealing Representation of Genome: Oligostickiness Map

نویسندگان

  • Ayumu Saito
  • Koichi Nishigaki
چکیده

A physicochemical property, stickiness, had been introduced by Nishigaki and Sakuma [1] to characterize the behavior of a molecule in a particular environment. As a convenient derivative of stickiness, oligostickiness was devised, which is closely related to the affinity of an oligonucleotide to a relevant DNA. In this paper we report that oligostickiness-maps, which can be generated by drawing a bar of the height proportional to the frequency of oligostickiness per window at the corresponding site along the (genome) circle, seem to show the relationship between the structure and the function of a genome DNA.

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تاریخ انتشار 2001